Atopie

Klinische Bedeutung

Als „Atopie“ wird die angeborene Neigung zu vermehrten allergischen Überempfindlichkeitsreaktionen bezeichnet, die klinisch unterschiedlich ausgeprägt sein kann. Die ursächlichen Allergene gelangen entweder über die Luft und die Schleimhäute in den Körper (bei Inhalationsallergien) oder im Zuge der Nahrungsaufnahme (bei Nahrungsmittelallergien).

Diagnostik

Zur Abklärung von Mehrfach-Sensibilisierungen bietet EUROIMMUN verschiedene Atopieprofile (EUROLINE, EUROASSAY) an. Diese ermöglichen die simultane In-vitro-Bestimmung unterschiedlicher humaner IgE-Antikörper gegen die häufigsten Inhalations- und Nahrungsmittelallergene in Serum oder Plasma. Darüber hinaus sind länderspezifische Profile verfügbar, welche die Besonderheiten der regionalen Allergenexposition berücksichtigen.


Zusätzlich kann mit dem Gesamt-IgE-ELISA die Gesamt-IgE-Konzentration bestimmt werden.

Nachweismethoden

Methode
Parameter
Substrat
ChLIA
IDS Positive Specific IgE Control (F003) Cod
1
2 x 1.2mL Control 1
ChLIA
IDS Positive Specific IgE Control (G006) Timothy Grass
1
2 x 1.2mL Control 1
ChLIA
IDS Negative Specific IgE Control (F003/G006) Cod/Timothy Grass
1
2 x 1.2mL Control 1
ChLIA
IDS Total IgE Control Set
1
1 x 1.2mL Control 1/2/3
EUROLINE
atopy "Chile 1"
(d1, d2, e1, e2, es2, g2, g4, g5, m2, m3, m6, t11, t14, t15,
t19, w9, w100, f1, f75, f78, f2, f40, f41, fs12, f4, f9, f13,
f14, f25, f33, f49, f92, f83, f96, f292,CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy "Chile 2"
(d1, d2, e1, e2, es2, gs2, m5, i6, t1, t7, t11, t14, t19, ts30,
ws23, f1, f2, f4, f6, f7, f13, f17, f36, f256, f14, f74, f105,
f292, f26, f27, f83, f88, f3, f40, f41, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy "Ukraine 2"
(d1, d2, e1, e2, e3, g6, t3, w6, m2, m3, f1, f75,
f2, f3, f4, f13, f14, f31, f35, f49, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy "Venezuela 1"
(f1, f75, f3, f24, f40, f308, f4, f5, f6, f7, f9, f14, f292, f79, f13,
f17, f20, f2, f76, f77, f78, f105, f218, f25, f32, f33, f44, f49,
f72, f26, f27, f83, f155, f45, u85, d1, d2, d201, e1, e2, e85,
m1, m2, m3, m5, m6, g2, w8, i1, i3, i70, i71, i100, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy "Caribbean 1"
(g6, g12, t3, t20, w6, e1, e2, e3, d1, m2, m6, f1, f2, f26, f79,
f4, f9, f14, f13, f31, f35, f292, f49, f3, f24, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy "Indonesia 1"
(g2, g6, gs1, t19, t223, u85, d1, d2, d4, d72, d73, d201, e1, e2,
e3, e204, es2, u134, i1, i6, m5, ms1, f4, f79, f13, f14, f17, f20,
f45, f336, f1, f2, f76, f77, f78, fs10, f3, f40, f41, f23, f24, f80,
f157, f63, f64, f83, f88, f81, f25, f47, f44, f84, f74, f105, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy "Thailand 1"
(g2, g6, g10, e1, e2, e84, d1, d2, i6, i100, m2, m3, m6, u85, f1,
f75, f2, f3, f23, f24, f41, f177, f234, f258, f232, f233, f76, f77,
f78, f4, f79, f13, f423, f427, f14, f36, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy "Thailand 2"
(d1, d2, e1, e2, e71, e82, e84, e85, e86, u81, u85, g2, g6, g10,
t18, t19, i6, i100, m1, m2, m3, m6, f1, f75, f2, f4, f10, f13, f14,
f20, f158, f31, f35, f45, f336, f23, f24, f234, f40, f41, f3, f436,
f324, f37, f258, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy
(g6, g12, t3, w6, d1, e1, e2, e3, m2, m6, f1, f2,
f3, f4, f9, f14, f17, f31, f35, f49, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
Atopy: 13
(d1, d2, d4, t2, t3, t4, t15, gs2, w6, w9, e1,
e2, e3, m1, m2, m3, m6, f13, f17, f20, f144,
f158, f256, f4, f5, f11, f99, f10, f14, f1, f75,
f2, f76, f77, f78, f3, f84, f49, f25, w1, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy 4
(f13, f17, f12, f14, f4, f85, f96, f26, f3, f24,
f1, f2, f49, f84, f95, t3, t7, t9, t11, t15, t23,
g6, w1, w6, w9, w21, e1, e5, m3, m6,
d1, d2, i6, CCD)
membrane strip with allergens
(EUROLINE)
EUROASSAY
pediatrics/atopy
(g6, g12, t3, w6, d1, d2, e1, e2, e3, m2, m3,
m6, f1, f75, f3, f2, f76, f77, f78, e204, f4, f9,
f14, f13, f17, f31, f35, f49, CCD)
EUROASSAY strip
with allergens
EUROLINE
pediatrics
(gx, t3, w6, d1, d2, e1, e2, e3, m2, m3, m6, f1, f75, f2, f3,
f76, f77, f78, e204, f4, f9, f14, f13, f17, f31, f35, f49, CCD)
membrane strip with allergens
(EUROLINE)
EUROASSAY
pediatrics/atopy 2
(t3, t4, t15, t2, gx2, g12, d1, w6, w1, d2, e1,
e2, m6, m2, f1, f13, f5, f2, f14, f4, f25, f85,
f31, f33, f92, f49, f17, f3, CCD)
EUROASSAY strip
with allergens
EUROLINE
atopy "China"
(ts20, w1, w6, ds1, h1, e1, e2, i6, ms1, u80, f1, f2, f13,
f14, f27, f88, fs33, f24, f23, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy "China 5"
(ds1, h1, i6, e1, e2, ms1, w1, w6, f1, f2, f13,
f14, f23, f24, fs33, u80, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy "China 7"
(ds1, h1, i6, e1, e2, ms1, w1, w6,
f1, f2, fs33, u80, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy "South East Asia 3"
(ts20, w1, w6, ds1, h1, e1, e2, i6, ms1, u80, f1, f2, f13,
f14, f27, f88, fs33, fs34, f24, f23, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy "Peru"
(e1, e2, e3, e11, e82, e84, es173, i1, i3, i6, m1, m2,
m3, m6, t18, u85, w29, d1, d2, f75, f79, f1, f2, f23,
f206, f13, f14, f104, f26, fs32, f44, f49, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy "Lithuania"
(w6, w9, w103, w203, t3, t4, t11, g6, gs21, e1, e2, e3, e4,
e82, es2, ds1, ms1, m5, f245, f2, f81, f13, f14, f17, f256, f4,
f12, f15, f44, fs32, f26, f27, f83, f49, f3, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy "Latin America 1"
(d1, d2, d201, h1, i71, i100, m1, m2, m3, m5,
m6, g2, g6, t3, ts26, ws23, e1, e2, e3, f4,
f6, f7, f9, f104, f1, f75, f3, f40, f41, f2, f78,
f77, f76, f23, f24, f25, f31, f35, f96, f14, f13,
f256, f26, f27, f83, f33, f44, f49, f72, f84, f92,
f93, f95, f329, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
atopy screen
(d1, d2, i1, i3, i6, h1, e1, e2, e3, m1, m2, m3, m6, g1, g3,
g6, g12, t2, t3, t4, t7, t23, w1, w6, w9, u85, f25, f31, f35,
f85, f1, f75, f2, f3, f23, f24, e204, f76, f77, f78, f27, f88,
f45, f4, f5, f9, f14, f10, f13, f17, f20, f49, f84, f237, CCD)
membrane strip with allergens
(EUROLINE)
EUROASSAY
DPA-Dx pediatrics 1
(t215, f76, f77, f78, e204, f232, f233, f323,
f356, f422, f423, f424, f427, CCD)
EUROASSAY strip
with allergens
EUROLINE
DPA-Dx pediatrics 2
(f76, f77, f78, f334, e204, f232, f233, f323, f356, f422,
f423, f424, f429, f445, f444, f427, t215, CCD)
membrane strip with allergens
(EUROLINE)
ChLIA
IDS Total / Specific IgE Reagent Kit

1
magnetic particles
ELISA
total IgE
antigen-coated
microplate wells
ChLIA
IDS Specific IgE (D001) House dust mite

1
allergen
ChLIA
IDS Specific IgE (D002) House dust mite

1
allergen
ChLIA
IDS Specific IgE (D202) rDer p 1

1
allergen
ChLIA
IDS Specific IgE (D203) rDer p 2

1
allergen
ChLIA
IDS Specific IgE (D205) rDer p 10

1
allergen
ChLIA
IDS Specific IgE (E001) Cat dander

1
allergen
ChLIA
IDS Specific IgE (E003) Horse dander

1
allergen
ChLIA
IDS Specific IgE (E005) Dog dander

1
allergen
ChLIA
IDS Specific IgE (E094) nFel d 1

1
allergen
ChLIA
IDS Specific IgE (E101) nCan f 1

1
allergen
ChLIA
IDS Specific IgE (F001) Egg white

1
allergen
ChLIA
IDS Specific IgE (F002) Cow's Milk

1
allergen
ChLIA
IDS Specific IgE (F003) Fish (cod)

1
allergen
ChLIA
IDS Specific IgE (F013) Peanut

1
allergen
ChLIA
IDS Specific IgE (F014) Soybean

1
allergen
ChLIA
IDS Specific IgE (F017) Hazelnut

1
allergen
ChLIA
IDS Specific IgE (F020) Almond

1
allergen
ChLIA
IDS Specific IgE (F037) Mussel

1
allergen
ChLIA
IDS Specific IgE (F075) Egg yolk

1
allergen
ChLIA
IDS Specific IgE (F076) Alpha-lactalbumin

1
allergen
ChLIA
IDS Specific IgE (F077) Beta-lactoglobulin

1
allergen
ChLIA
IDS Specific IgE (F078) Casein

1
allergen
ChLIA
IDS Specific IgE (F084) Kiwi

1
allergen
ChLIA
IDS Specific IgE (F202) Cashew nut

1
allergen
ChLIA
IDS Specific IgE (F203) Pistachio

1
allergen
ChLIA
IDS Specific IgE (F233) nGal d 1

1
allergen
ChLIA
IDS Specific IgE (F245) Hen's Egg

1
allergen
ChLIA
IDS Specific IgE (F256) Walnut

1
allergen
ChLIA
IDS Specific IgE (F351) rPen a 1

1
allergen
ChLIA
IDS Specific IgE (F423) rAra h 2

1
allergen
ChLIA
IDS Specific IgE (F427) rAra h 9

1
allergen
ChLIA
IDS Specific IgE (F428) rCor a 1

1
allergen
ChLIA
IDS Specific IgE (F434) rMal d 1

1
allergen
ChLIA
IDS Specific IgE (G002) Bermuda grass

1
allergen
ChLIA
IDS Specific IgE (G003) Cocksfoot

1
allergen
ChLIA
IDS Specific IgE (G004) Meadow fescue

1
allergen
ChLIA
IDS Specific IgE (G005) Rye-grass

1
allergen
ChLIA
IDS Specific IgE (G006) Timothy grass

1
allergen
ChLIA
IDS Specific IgE (G007) Common reed

1
allergen
ChLIA
IDS Specific IgE (G008) Meadow grass

1
allergen
ChLIA
IDS Specific IgE (G012) Cultivated rye

1
allergen
ChLIA
IDS Specific IgE (G013) Velvet grass

1
allergen
ChLIA
IDS Specific IgE (G014) Cultivated oat

1
allergen
ChLIA
IDS Specific IgE (G015) Cultivated wheat

1
allergen
ChLIA
IDS Specific IgE (G201) Barley

1
allergen
ChLIA
IDS Specific IgE (G205) rPhl p 1

1
allergen
ChLIA
IDS Specific IgE (G213) rPhl p 1, rPhl p 5b

1
allergen
ChLIA
IDS Specific IgE (G215) rPhl p 5b

1
allergen
ChLIA
IDS Specific IgE (GX03) Grass mix 3

1
allergen
ChLIA
IDS Specific IgE (I001) Honey bee

1
allergen
ChLIA
IDS Specific IgE (I003) Wasp

1
allergen
ChLIA
IDS Specific IgE (K082) Latex

1
allergen
ChLIA
IDS Specific IgE (M003) Aspergillus fumigatus

1
allergen
ChLIA
IDS Specific IgE (M006) Alternaria alternata

1
allergen
ChLIA
IDS Specific IgE (M229) rAlt a 1

1
allergen
ChLIA
IDS Specific IgE (T002) Alder

1
allergen
ChLIA
IDS Specific IgE (T003) Common silver birch

1
allergen
ChLIA
IDS Specific IgE (T004) Hazel

1
allergen
ChLIA
IDS Specific IgE (T009) Olive

1
allergen
ChLIA
IDS Specific IgE (T025) European ash

1
allergen
ChLIA
IDS Specific IgE (T215) rBet v 1

1
allergen
ChLIA
IDS Specific IgE (T216) rBet v 2

1
allergen
ChLIA
IDS Specific IgE (T224) rOle e 1

1
allergen
ChLIA
IDS Specific IgE (W001) Common ragweed

1
allergen
ChLIA
IDS Specific IgE (W006) Mugwort

1
allergen
ChLIA
IDS Specific IgE (W009) Plantain

1
allergen
ChLIA
IDS Specific IgE (W230) nAmb a 1

1
allergen
ChLIA
IDS Specific IgE (W231) nArt v 1

1
allergen
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